The ventilatory ratio (VR) is a dimensionless index that reflects the efficiency of CO₂ elimination. A value >1 indicates dead space ventilation or increased metabolic CO₂ production, while <1 suggests hyperventilation.
Clinical Note: In ARDS patients, VR >2 is associated with higher mortality and may indicate significant dead space ventilation.
VR = [Minute Ventilation × PaCO₂] / [PBW × 100 × 37.5]
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